Sandeep K. Mallipattu, MD, FASN

Grants Review Committee

Our primary research program focuses on the mechanism(s) by which Kruppel-Like Factors (KLFs) and their downstream signaling in regulating fundamental cellular processes in the kidney, as it relates to regulation of cell differentiation and metabolism. We are also investigating the role of KLFs in the developing kidney and cell regeneration. Furthermore, we are currently using novel in vitro and in vivo approaches to establish the physiological and pathophysiological functions of KLFs in various disease processes (Diabetic Kidney Disease, Focal Segmental Glomerulosclerosis, acute kidney injury transition to kidney fibrosis); as well as high-throughput screening strategies to identify small molecular compounds that might serve as novel therapeutic agents in disease based on their ability to modulate the expression and function of KLFs.

Current Position/Titles:

DCI-Liebowitz Endowed Professor of Medicine, Stony Brook University

Chief, Division of Nephrology & Hypertension, Stony Brook Medicine

Director, Long Island Network of Clinical and Translational Science (LINCATS) Career Development Program, Stony Brook Medicine

Degrees/Training:

B.Sc., Biomedical Engineering, University of California, San Diego, La Jolla, CA

M.D., Boston University, Boston, MA

Internal Medicine Residency: Icahn School of Medicine at Mount Sinai, NY, NY

Nephrology Fellowship: Icahn School of Medicine at Mount Sinai, NY, NY

Research/Postdoctoral Training: Icahn School of Medicine at Mount Sinai, NY, NY

Leadership positions:

Chief, Division of Nephrology & Hypertension (2018-current); Director of the Long Island Network for Clinical and Translational Science Mentored Career Development Program (2021-current); Clinically Integrated Network, Accountable Care Organization, Board Member (2021-2024); NIH/NIDDK Institute-Wide Strategic Planning Group (Stewardship Working Group) (2021); Chair, International Society of Nephrology - World Congress of Nephrology Abstract Session: Experimental Models- Glomerulonephritis (2022); Chair, Enhancing Research Productivity Working Group (Financial Sustainability Steering Committee, Office of President, Stony Brook University) (2021); Chair, Department of Medicine Strategic Planning Meeting, Stony Brook Medicine (2019).

Study Sections & Editorial Boards: Standing member, NIH/NIDDK Pathobiology of Kidney Disease, Center for Scientific Review (2021-2025); Standing member, Veterans Affairs BL&CS R&D Merit Review - Nephrology Subcommittee, (2017-current); Standing member, NIH/NIDDK DDK-D Kidney, Urology, and Hematology (KUH) fellowship (2019-2022); Chair, NIH ZRG1 KUDS-L 91 S, Topics in Nephrology (Special Emphasis Panel) (2024); French National Research Agency Review Panel AAPG (Physiology, Pathophysiology) (2025); Diabetes United Kingdom Review Panel (2024); Reviewer, Diversity, Equity, and Inclusion Review (DEIR), Veterans Affairs BL&CS R&D, Subcommittee (2024); Editorial Board: Diabetes (2023-current); Guest Associate Editor: American Journal of Physiology-Renal Physiology (2023); Veterans Affairs ZRD1 SPLJ-C (01) 1 - ShEEP, ShEEP-iC, LAMb (2021); Chair, NIH ZRG1 KUDS-L 91 S, Topics in Nephrology (2024); Co-Chair, NIH/NIDDK Nephrology Small Business ZRG1 DKUS-L (2019); NIDDK Diabetes Complications Consortium Review Committee (Pilot & Feasibility Applications) (2019); Special Emphasis Panel (SEP) Study Section [ZRG1-EMNR-F(50)R]- (Early-Stage Preclinical Validation of Therapeutic Leads for Diseases of Interest to the NIDDK) (2018-2019); NephCure-Neptune Ancillary Grant and CureGN Pilot Project Review Committee (2019-2021).

Honors:

Provost’s Outstanding Mentor Award, Stony Brook University (2024); Faculty Mentoring Award, School of Medicine, Stony Brook University (2023); American Society of Clinical Investigation (ASCI) – Elected member (2023); Clinical Scientist Investigator Award, Veterans Affairs (2022); Presidential Early Career Award for Scientists and Engineers (PECASE) (2019); Discovery Prize Finalist, Stony Brook University (2019); Department of Medicine Faculty Mentorship Award, Stony Brook University (2019); Fellow of American Society of Nephrology (2018); Department of Medicine Faculty Research Award, Stony Brook University (2015); American Society of Clinical Investigation Young Physician-Scientist Award (2015); Phi Beta Kappa, University of California, San Diego (2002); Tau Beta Pi, University of California, San Diego (2000).

ASN Service:

My contributions to ASN Service include the following: (1) ASN Grant Review Committee (Ben J. Lipps Research Fellowship Program and Transition to Independence Grant applications) in 2025. (2) Serving on the Annual ASN Kidney Week Abstract Selection Member for multiple years in 2015-2024. (3) ASN-TREKS (Tutored Research and Education for Kidney Scholars) for multiple years in 2018-2024. (4) ASN Kidney STARS program mentor from 2017-2024. (5) Serving as Journal of American Society of Nephrology Peer Reviewer for multiple years from 2015-2024. (6) ASN Kidney Week Moderator from 2017-2020, 2023-2024. (7) Keynote Speaker for ASN Kidney Stars: Bridge the Gap for Graduate Students. ASN Kidney Week in 2024. (8) ASN Kidney Week Speaker in 2019, 2020, 2022, and 2024.

Board Certification:

Internal Medicine, Nephrology

Research Interests:

The mission of our research program is to investigate mechanisms that mediate the development and progression of kidney disease with the ultimate goal of identifying novel therapeutics. Specifically, our studies have contributed to advancing our understanding of fundamental gene regulatory processes required to maintain cellular homeostasis in the setting of kidney injury. This has led to identification of novel therapeutic targets in various disease processes such as Diabetic Kidney Disease, Focal Segmental Glomerulosclerosis, and the transition from Acute Kidney Injury to Kidney Fibrosis.

Personal Statement:

My experiences as a practicing nephrologist, scientist, leader, and mentor provide a strong foundation to serve on the ASN council. I have dedicated my career to improving kidney health through research, patient education and advocacy, and mentoring the next generation of scientists and nephrologists. Challenges to recruitment and retention of trainees, patient advocacy, physician well-being, and research funding remain at the forefront in our field. I would be honored to develop and implement timely strategic initiatives to help directly address these challenges with the American Society of Nephrology.