Leslie S. Gewin, MD
Grants Review Committee
Leslie Gewin, M.D. is a physician-scientist at Washington University in St. Louis who received her medical training at University of Alabama at Birmingham. She completed an internal medicine residency at Johns Hopkins Medical Institute and her nephrology fellowship at Vanderbilt University Medical Center. Dr. Gewin attends on the nephrology consult service and nephrology clinic at the St. Louis VA. She also runs a basic science laboratory that focuses on better understanding the mechanisms of renal tubular injury and repair. Dr. Gewin's laboratory has received funding from both the VA and NIH and focuses on how growth factors (e.g. TGF-beta, Wnt/beta-catenin) and changes in metabolism alter the epithelial response to renal injury. Her lab uses mouse injury models as well as cell culture techniques to better understand the adaptive and pathophysiologic responses of renal tubules to various insults. In addition, Dr. Gewin is interested in training and promoting career development of future investigators.