Carl W. Gottschalk Research Scholar Grant Recipients


Cary R. Boyd-Shiwarski, MD, PhD
The role of calcineurin inhibitors on blood pressure and potassium homeostasis through WNK body molecular condensates

Georgina Gyarmati, MD, MPH
Role of the newly discovered neuroendothelial cells in renal physiology and disease

Matthew Bruce Lanktree, MD, PhD, FASN
Multi-omics in PEXIVAS: using precision medicine to improve risk stratification in ANCA Vasculitis

Yoshiharu Muto, MD, PhD
Role of methionine cycle in remodeling of epigenetic landscape in acute kidney injury and failed repair

Insa Marie Schmidt, MD, MPH
A deep learning framework for the automated assessment of kidney pathology and prognosis

Anand Srivastava, MD, MPH
Functional MRI for Enhanced Phenotyping of CKD


Leo Francis Buckley, PharmD, MPH
Pharmacoproteomic Investigation of Colchicine Pharmacology in Chronic Kidney Disease

Florian Buerger, MD, PhD
Delineating the role of secreted semaphorin 3G in monogenic and acquired glomerulopathies and studying its potential protective effect for the kidney's glomerular filtration barrier.

Eman Y. Gohar, MS, PhD
Intrarenal Estrogen Biosynthesis as a Novel Regulator of Renal Sodium Handling

Vivek Kasinath, MD
Targeted Nanotherapeutics for Renal Cell Carcinoma

Kenneth Lim, MD, PhD, FASN
Translating biological discoveries in Klotho into a therapeutic strategy for CKD-associated cardiac fibrosis.

Sandhya S. Thomas, MD, FASN
SIRP? Mediates Insulin/IGF1 Receptor Signaling in CKD-Induced Cardiomyopathy

Clintoria R. Williams, PhD
Renoprotective Properties of Zinc Supplementation in Chronic Kidney Disease


Eirini Kefalogianni, PhD
Immunomodulatory roles of circulating TNFR1/2 in diabetic nephropathy

Ronak Lakhia, MD
Role of Cis-Regulatory Elements in Autosomal Dominant Polycystic Kidney Disease

Eugene Lin, MD, MS, FASN
The Impact of Medicare Advantage on Patients with End-Stage Kidney Disease

Jennie Lin, MD, MS, FASN
Endoplasmic Reticulum Stress and Macrophage Function in APOL1 Nephropathy

Alla Mitrofanova, PhD
STING as a potential therapeutic target for diabetic kidney disease

Evan C. Ray, MD, PhD, FASN
Regulation of Divalent Cation Homeostasis by Muc1

Yanhua Wang, PhD
Roles of aldosterone and phosphatases in vasopressin escape


Mark R. Hanudel, MD, MS, FASN
The Pathologic Effects of Fibroblast Growth Factor 23 Fragments

Sho Morioka, PhD
Boosting apoptotic cell removal during acute kidney injury

Sanjeev Noel, PhD
T cell TIGIT/CD226 co-signaling in acute kidney injury and repair

Jin Wei, PhD
Role of macula densa RXFP1 in gestational hypertension

Ting Yang, MD, PhD
Renal epithelial actions of the prostaglandin EP4 receptor in blood pressure control

Jie Zhang, PhD
A new mechanism for the sex differences in diabetic glomerular hyperfiltration and kidney injury


Subhashini Bolisetty, PhD
Targeting ferritin in sepsis-associated acute kidney injury

Louise Christine Evans, PhD
Pathological role of T-cells in salt-sensitive hypertension

Naoka Murakami, MD, PhD, FASN
Roles of immune checkpoint signaling in autoimmune kidney diseases

Sagar U. Nigwekar, MD
Novel Determinants of Calcific Uremic Arteriolopathy

Tengis S. Pavlov, PhD
Mechanism and role of ATP release in polycystic kidney diseases

Fahad Saeed, MD, FASN
Pilot Testing of a Communication Intervention to Promote Shared Renal Replacement Therapy Decision Making in Older Patients with Chronic Kidney Disease (RRT- SDM Trial)

Tomokazu Souma, MD, PhD
Harnessing Antioxidative Stress Pathways in Renal Epithelial Progenitors to Prevent AKI-to-CKD Transition


Alexander Grabner, MD
The Role of FGF23 and FGFR4 in Cardio-renal Syndrome

Hana A. Itani, PhD, FASN
New Immune Mechanisms in Hypertension

David E. Leaf, MD, MMSc, FASN
Hepcidin, Dysregulated Iron Homeostasis, and Anemia in Human Acute Kidney Injury

Ali Poyan-Mehr, MD
Metabolic And Molecular Predictors of Acute Kidney Injury in Humans and Their Clinical Response to NAD+ Augmentation

Roderick J. Tan, MD, PhD
Tubular-to-Glomerular Crosstalk in Proteinuric Chronic Kidney Disease

Brandi M. Wynne, PhD
Renal Dendritic Cell-Derived Interleukin 6 Increases Sodium Reabsorption and Blood Pressure


Amandeep Bajwa, PhD
Mitochondria Transfers to Prevent Ischemic Reperfusion Injury in Transplant

Wei Chen, MD, MS, FASN
Calcification Propensity, using Dynamic Light Scattering, to Study Vascular Calcification in Patients with Advanced Chronic Kidney Disease

Paul G. DeCaen, PhD
Defining ADPKD-2 Mutation Effects on Ciliary PKD2 Ion Channels

Kevin F. Erickson, MD, MS, FASN
Dialysis Facility Closures and their Effect on Costs, Health Outcomes, and Access to Care

Nicholas J. Ferrell, PhD
Extracellular matrix-mediated mechanotransduction in diabetic nephropathy

Aaron J. Polichnowski, PhD
Deleterious Effects of TNF-α on the AKI-CKD Nexus


Jennifer R. Charlton, MD, MS
Detecting renal pathology in mouse model of prematurity using MRI-based biomarkers

Benjamin S. Freedman, PhD
Modeling Human Kidney Disease with Pluripotent Stem Cells

Sarah C. Huen, MD, PhD
The Role of Kidney FGF21 in Surviving Sepsis

Sang-Ho Kwon, MS, PhD
Exosome biogenesis in renal tubule growth and acute kidney injury

Joshua M. Stern, MD
Evidence for a Distinct Gut Microbiome in Kidney stone patients

Crystal A. West, PhD
Proteinase-activated receptor 2 (PAR2) in the altered renal electrolyte handling of pregnancy


Mitsi A. Blount, PhD
Compartmentalized Regulation of Urea Permeability in the Inner Medullary Collecting Duct

Paul E. Drawz, MD, MS
Treatment of Masked Hypertension

Nadja Grobe, PhD
Molecular Imaging of the Renin Angiotensin System for the Discovery of Novel Biomarkers in Chronic Kidney Disease

Mark Parker, PhD
Cause and Consequence of Acidosis by the Sodium/bicarbonate Cotransporter NBCe1

Nirupama Ramkumar, MD, FASN, MPH
Functional Role of Nephron Prorenin Receptor in Regulation of Blood Pressure, Sodium and Water Homeostasis

Matt G. Sampson, MD
Genetic Risk in Nephrotic Syndrome from an Integrative Genomics Approach

Jennifer M. Sasser, PhD
Mechanisms and Mediators of the Preeclamptic Phenotype in the Dahl S Rat


Michael Butterworth, PhD
Aldosterone-Regulated MicroRNAs and Sodium Transport in the Distal Kidney Nephron

Kirk N. Campbell, MD, FASN
Role of Dendrin in Glomerular Disease Progression

Krzysztof Kiryluk, MD
GWAS-based Pathogenesis Model of IgA Nephropathy

Timmy C. Lee, MD, FASN, MPH
Natural History of Arteriovenous Fistula Maturation

Ethan P. Marin, MD, PhD
A Novel Mode of Vascular Function Regulation by Protein Palmitoylation

Brian B. Ratliff, PhD
Posttranslational and Redox Modification Regulation of HMGB1 During Kidney Injury

Matthias Tilmann Wolf, MD, PhD, FASN
The Role of Mucin 1 in Protection Against Nephrolithiasis by Regulation of the Renal Calcium Channel TRPV5


Matthew K. Abramowitz, MD, MS, FASN
Metabolic Acidosis and Insulin Resistance in Chronic Kidney Disease

Michelle L. Gumz, PhD
Role of the Kidney in Blood Pressure Regulation by the Circadian Protein Per1

Tamara Isakova, MD, MMSc
Longitudinal Assessments of Sclerostin in Chronic Kidney Disease

Pinelopi P. Kapitsinou, MD
Role of Endothelial Oxygen Sensing in Kidney Injury and Repair

Mara McAdams-DeMarco, PhD
Frailty and Adverse Health Outcomes of Aging in Older Adults with Kidney Failure

Jennifer L. Pluznick, PhD
Elucidating the Function of Renal Olfactory Receptor 1393

Aylin R. Rodan, MD, PhD, FASN
Mechanisms of NKCC Regulation in the Drosophila Renal Tubule


Christian Faul, PhD
The Role of Fibroblast Growth Factor 23 in Cardiorenal Syndrome

Puneet Garg, MD, FASN
Shp2 a Non-receptor Tyrosine Phosphatase Regulates Nephrin Phosphorylation and Podocyte Mobility

Michal L. Melamed, MD
Vitamin D and Cardiovascular Risk Factors in Kidney Disease

Farzana Perwad, MD
Role of FGF-23 in Cardiovascular Complications in Chronic Kidney Disease

Rosemary V. Sampogna, MD, PhD
Circadian Clock Genes as Determinants of Kidney Architecture, Nephron Number and Hypertension

Weibin Zhou, PhD
Zebrafish Model of Steroid-Sensitive Nephrotic Syndrome


Kerri L. Cavanaugh, MD, MHS, FASN
Targeting Social Determinants to Improve Chronic Kidney Disease Care

Anna Greka, MD, PhD
Regulation of Podocyte Actin Dynamics by Angiotensin/TRPC Channel Signaling

Hatim A. Hassan, MD, PhD, FASN
Leptin Signaling and Oxalate Hemostasis: Relevance to Calcium Oxalate Kidney Stone Disease

Oleh Pochynyuk, PhD
Purinergic Control of Mechano-Sensitivity in the Distal Nephron

Bernd Schroppel, MD
Immune Regulatory Mechanisms of Autophagy During Transplantation Tolerance

Pamela Vivian Tran, PhD
Molecular Mechanism of THM1-Mediated Renal Cystogenesis

Shao-Ling Zhang, PhD
Role of Reactive Oxygen Species (ROS) in Maternal Diabetes-Induced Perinatal Programming


Vivek Bhalla, MD, FASN
Molecular Mechanisms of Salt-Sensitive Hypertension in Insulin Resistance

David M. Charytan, MD, MS, MSc
Microvascular Density in the Hearts of Individuals with and without CKD: Invasive and Non-Invasive Studies

Paolo Fiorina, MD
B7.1 on Podocytes: A New Therapuetic Target for Diabetic Nephropathy

Akio Kobayashi, PhD
Genetic Regulation of Nephron Progenitor Cells

Vladimir Pech, MD
The Role of HCO3- in ENaC Regulation

Timo Rieg, MD, PhD
Role of Big Conductance K Channels in K Secretion

Simone Sanna-Cherchi, MD
Search for Rare Structural Variants in Kidney and Urinary Tract Malformations


Francesca Di Sole, PhD
Adenosine A1 Receptor Activation Regulates Salt and Fluid Homeostasis: A Novel Adaptive Mechanism in Acute Ischemia/Reperfusion Injury

William Henry Fissell, MD
Could the GBM be the Filtration Barrier? Pressure, Permeability, and the ECM

Benjamin D. Humphreys, MD, PhD, FASN
The Role of Indian Hedgehog in Recovery from Acute Kidney Injury

Sung Il Kim, PhD
Role of TGF-Beta-Activated Kinase 1 (TAK1) in TGF-Beta-Induced ECM Remodeling and Renal Cell Death

X. Sean Li, MD
Formation And Maintenance of Renal Epithelial Cells

Hua Ann Jenny Lu, MD, PhD, FASN
Novel Function of AQP2 on Kidney Tubulogenesis

Uptal D. Patel, MD
Impact of Automated Reporting of Kidney Function in the Veterans Affairs Healthcare System

Ganesan Ramesh, PhD
Regulation of Inflammation By Netrin-1 In Ischemia Reperfusion Injury Of The Kidney

Johannes S. Schlondorff, MD, PhD
Mechanisms of TRPC6-Mediated Podocytopathy

Shuxia Wang, MD, PhD
Protective Role of PKG in Renal Ischemia-Reperfusion Injury

Daniel E. Weiner, MD, MS, FASN
Medical, Economic and Ecologic Implications of Dialyzer Reprocessing

Jing Yu, PhD
Molecular Regulation of Mammalian Renal Medulla Formation


Brian D. Adair, PhD
Structure Analysis in PKD2 Membrane Channels

Markus Bitzer, MD
TGF-b and MicroRNAs in Renal Disease

Ion Alexandru Bobulescu, MD
Reulgation of the Renal Sodium/Proton Exchanger NHE3 by Dopamine: Role of Protein Phosphatase 2A

Tarek M. El-Achkar, MD, FASN
A Novel Protective Role for Tamm-Horsfall Protein in Kidney Injury

Sarah Faubel, MD
The Role of IL-6 in Lung Injury after Acute Kidney Injury

Michal Mrug, MD
Role of Complement Component 3 in Polycystic Kidney Disease Pathogenesis

Samir M. Parikh, MD, FASN
PGC1-alpha in Septic Acute Kidney Injury

Alexander Staruschenko, PhD, FASN
Regulation of ENaC by Small G Proteins and Cytoskelton

Farook Thameem, PhD
Susceptibility Gene Search for GFR in Diabetes


Shuta Ishibe, MD
Role of Met Receptor in Kidney Development and Repair

Anil K. Karihaloo, PhD
Role of VEGF During Early Embroyonic Kidney Development

Susan M. Kiefer, PhD
Kidney and Ureter Abnormalities of Pax2/Sall4 Compound Mice

S. Todd Lamitina, PhD
Regulation of Osmotic Stress Responses by the MAP Kinase Gene Lit-1 in C. Elegans

Reena Rao, PhD
Contribution of Renal Collecting Duct Sodium Transport to the Metabolic Syndrome

Ikuyo Yamaguchi, MD, PhD
Regulation of the Renal Microvasculature by Placental Growth Factor and Vascular Endothelial Cadherin During Chronic Kidney Disease

Wenzheng Zhang, PhD
Generation and Characterizations of CNT/CD-Specific Dot1a-Deficient Mice as a Novel Liddle's Syndrome Model


Patrick Cunningham, MD, FASN
Mechanisms of Injury in Endotoxin Induced Acute Renal Failure

Jeremy Stuart Duffield, MD, MBChB, PhD
Macrophage Delivered Wnt Signaling in the Development of Progressive Fibrosis in the Kidney

Kenneth R. Hallows, MD, PhD, FASN
Mechanisms of Epithelial Na Channel Regulation by AMP-Activated Protein Kinase

Fangming Lin, MD, PhD, FASN
Isolation and Characterization of Murine Renal Stem/Progenitor Cells

Zubaida R. Saifudeen, PhD
Role of p53 in Early Kidney Development

Michael Zeisberg, MD
The Role of integrinI in Epithelial-Mesenchymal Transition in Renal Fibrosis


Thomas J. Carroll, PhD

Stephen I-Hong Hsu, MD, PhD

Timothy A. Sutton, MD, PhD, FASN


Robyn A. Cunard, MD

Neil A. Hukriede, PhD

Snezana Petrovic, MD, MEd, PhD, FASN


Dorin-Bogdan Borza, PhD

Yumay Chen, PhD

Christine Maric-Bilkan, PhD, FASN


Patrick D. Brophy, MD

Sumant S. Chugh, MD, FASN

S. Ananth Karumanchi, MD

Janos Peti-Peterdi, MD, PhD


Carlton M. Bates, MD

Zheng Dong, PhD, FASN

James D. Stockand, PhD, FASN


John M. Arthur, MD, PhD, FASN

Rulan S. Parekh, MD, MS, FASN


Jeffrey C. Fink, MD, MS, FASN

Susan E. Quaggin, MD, FASN


Raghu Kalluri, MD, PhD, FASN

Alan S.L. Yu, MBChB


Bradley K. Yoder, PhD


Jonathan M. Barasch, MD, PhD